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spiedigitallibrary.org
Ibuprofen-nicotinamide cocrystal polymorphs: terahertz spectroscopy and DFT calculations
In this paper, two IBU-NIC cocrystal polymorphs of ibuprofen (IBU) and nicotinamide (NIC) were synthesized by melt recrystallization, solution evaporation and solvent milling, respectively. IBU, NIC, physical mixtures and their corresponding two cocrystals were characterized by terahertz (THz) spectroscopy. In addition, the theoretical ...
Nov 8, 2024
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