p53 and Cell cycle arrest |Cancer Biology | Oncology ‪@biologyexams4u‬
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p53 and Cell cycle arrest |Cancer Biology | Oncology ‪@biologyexams4u‬
How p53 induces cell cycle arrest in DNA damaged cells? Pathway Explained http://www.biologyexams4u.com/2013/08/how-p53-induces-cell-cycle-arrest-in.html p53 'Guardian of the genome' and 'Policeman of the Oncogenes' http://www.biologyexams4u.com/2013/08/p53-guardian-of-genome-and-policeman-of.html How p53 induces apoptosis in DNA damaged cells ...
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p53 is the guardian of the genome. p53 knockout mice (-/-) are highly susceptible to formation of tumors. why? failure to detect or accurately repair DNA damage can lead to oncogenesis, particularly if the mutations are in genes controlling the cell cycle, metabolism, and/or apoptosis #biochem #molecularbiology #oncogenesis #p53 #biotok #premed
p53 is the guardian of the genome. p53 knockout mice (-/-) are highly susceptible to formation of tumors. why? failure to detect or accurately repair DNA damage can lead to oncogenesis, particularly if the mutations are in genes controlling the cell cycle, metabolism, and/or apoptosis #biochem #molecularbiology #oncogenesis #p53 #biotok #premed
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