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Rationale The most common antibiotic used to treat people with cystic fibrosis (PWCF) is inhaled tobramycin, administered as maintenance therapy for chronic Pseudomonas aeruginosa lung infections.

"Science means constantly walking a tight rope" Heinrich Rohrer, physicist, 1933. Community-acquired pneumonia (CAP) is the leading cause of death from infectious disease worldwide and ...

Introduction Current bronchiectasis guidelines advise against the use of inhaled corticosteroids (ICS) except in patients with associated asthma, allergic bronchopulmonary aspergillosis (ABPA) and/or ...

Academic Unit of Respiratory Medicine, Royal Free & University College Medical School, London, UK Correspondence to: Dr J R Hurst Academic Unit of Respiratory Medicine, Royal Free & University College ...

Background Eosinophil-derived neurotoxin (EDN) and eosinophil cationic protein (ECP) are proteins released by activated eosinophils whose role in adult asthma remains unclear. Objective To study ...

Otago and Canterbury Respiratory Research Groups, Dunedin and Christchurch Schools of Medicine, University of Otago Medical School, New Zealand Dr D R Taylor, Department of Medicine, Dunedin School of ...

2 Department of Clinical Parasitology, Hospital for Tropical Diseases, London, UK 3 Department of Respiratory Medicine, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK 4 ...

1 Department of Paediatrics, Oxford University Hospitals NHS Trust, Oxford, UK 2 Department of Paediatrics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK ...

It is not a novel observation that the clinical trial enterprise has largely been unsuccessful in finding new and effective treatments for the acute respiratory distress syndrome (ARDS).1 2 While a ...

Associations of pulmonary microvascular blood volume with per cent emphysema and CT emphysema subtypes in the community: the MESA Lung study ...

Correspondence to Børge G Nordestgaard, Professor, Chief Physician, Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev Ringvej 75, DK-2730 Herlev, Denmark; ...