BMJ

Early mortality in systemic vasculitis: relative contribution of adverse events and active vasculitis

1 Renal Institute of Birmingham, School of Infection, Immunity and Inflammation, College of Medicine and Dental Sciences, University of Birmingham, Birmingham, UK Objective To contrast the effect of ...
BMJ

Gout: why is this curable disease so seldom cured?

3 Department of Rheumatology, University of Edinburgh, Centre for Molecular Medicine, Western General Hospital, Edinburgh, Scotland, UK 4 Department of Medicine, Rheumatology Section, Alicante ...
BMJ

Epidemiology of whiplash: an international dilemma

562 Heritage Medical Research Centre, University of Alberta, Edmonton, Alberta, Canada TG6 2S2 Whiplash associated disorders have become an international medicolegal and social dilemma. Physicians are ...
BMJ

Withdrawal of low-dose prednisone in SLE patients with a clinically quiescent disease for more than 1 year: a randomised clinical trial

1 Sorbonne Université, Assistance Publique–Hôpitaux de Paris, Groupement Hospitalier Pitié–Salpêtrière, French National Referral Center for Systemic Lupus Erythematosus, Antiphospholipid Antibody ...
BMJ

Clinically important changes in individual and composite measures of rheumatoid arthritis activity: thresholds applicable in clinical trials

Correspondence to Dr Michael M Ward, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, NIAMS/NIH, Building 10 CRC, Room ...
BMJ

Psoriatic arthritis: epidemiology, clinical features, course, and outcome

1 University of Toronto, Toronto Western Research Institute, Psoriatic Arthritis Program, University Health Network, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, ...
BMJ

Power Doppler ultrasonography and synovitis: correlating ultrasound imaging with histopathological findings and evaluating the performance of ultrasound equipments

1 Department of Internal Medicine, Mikkeli Central Hospital, Mikkeli, Finland 2 Department of Nuclear Medicine, Mikkeli Central Hospital, Mikkeli, Finland 3 Department of Pathology, Mikkeli Central ...
BMJ

Pain and high sensitivity C reactive protein in patients with chronic low back pain and acute sciatic pain

Background: The severity of pain from musculoskeletal disorders might be associated with high sensitivity C reactive protein (hsCRP), a sensitive marker of low grade systemic inflammation. Objective: ...
BMJ

Gout is associated with more comorbidities, poorer health-related quality of life and higher healthcare utilisation in US veterans

Center for Chronic Disease Outcomes Research at the VA Medical Center, Minneapolis, Minnesota, USA Objective: To better understand the impact of gout on functional status, health-related quality of ...
BMJ

IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy

3 Department of Surgery and Anatomy, School of Medicine of Ribeirao Preto, University of Sao Paulo, Sao Paulo, Brazil 4 Division of Clinical Immunology, School of Medicine of Ribeirao Preto, ...
BMJ

Methotrexate in rheumatoid arthritis

Methotrexate (MTX) is a folate analogue originally synthesised in the 1940s and designed to inhibit dihydrofolate reductase.1 Reduced folate (tetrahydrofolate) is the proximal single carbon donor in ...
BMJ

Germline genetic patterns underlying familial rheumatoid arthritis, systemic lupus erythematosus and primary Sjögren’s syndrome highlight T cell-initiated autoimmunity

Objectives Familial aggregation of primary Sjögren’s syndrome (pSS), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and co-aggregation of these autoimmune diseases (ADs) (also called ...