BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

Beyond the realm of PAL-dependent techniques, Velagapudi and co-workers have recently described a method for the identification of RNA targets of small molecules through covalent ligation and ...

The rapid identification of respiratory virus outbreaks is needed to enable rational and effective public health interventions. We developed new quantitative approaches for simultaneous ...

Single-cell RNA-seq (scRNA-seq) has spent the past decade maturing into a foundational technology. Over that time, the ...

Scientists with the NIH-backed SMaHT Network are mapping every DNA mutation in the human body, creating a groundbreaking ...

The ability to analyze gene expression at the single-cell level—known as single-cell RNA sequencing (scRNA-seq)—has ...

Fred Hutch researchers have created a gene-expression map of glial cells of the tiny worm, C. elegans, adding the missing ...

Further, our single-cell RNA sequencing (scRNA-seq) data revealed that infection with SARS-CoV-2 rewired the gene expression profile of NK, monocytes, CD4 + , CD8 + effector T cells and antibody ...

While physical activity is known to slow cognitive decline in Alzheimer’s disease, many patients are unable to exercise due ...

Next-Generation Sequencing in bioinformatics produce a massive amount of data volume. Big data technologies are needed to reduce computation time in data processing. In this paper, we implement Hadoop ...

Negedia focuses on understanding an individual's genetic and molecular characteristics to make informed decisions about prevention, wellness and treatment. It is dedicated to researchers, specialists, ...