BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

The rapid identification of respiratory virus outbreaks is needed to enable rational and effective public health interventions. We developed new quantitative approaches for simultaneous ...

Single-cell RNA-seq (scRNA-seq) has spent the past decade maturing into a foundational technology. Over that time, the ...

Scientists with the NIH-backed SMaHT Network are mapping every DNA mutation in the human body, creating a groundbreaking ...

The ability to analyze gene expression at the single-cell level—known as single-cell RNA sequencing (scRNA-seq)—has ...

While physical activity is known to slow cognitive decline in Alzheimer’s disease, many patients are unable to exercise due ...

Negedia focuses on understanding an individual's genetic and molecular characteristics to make informed decisions about prevention, wellness and treatment. It is dedicated to researchers, specialists, ...

Here, we sought to circumvent the challenges of non-multiplexed bulk RNA-seq imposed by the scale and population heterogeneity by performing eQTL mapping through single-cell RNA sequencing (scRNA-seq) ...

CHICAGO – A new gene expression atlas developed using single-cell RNA sequencing data shows how normal hematopoietic cells differentiate and was used to catalog the multiple ways that aberrant ...

By creating comprehensive maps of the locations of gene expression in tissue, spatial transcriptomics technologies have made it possible to perform new types of biological assessments.

2023 Toward Sequencing and Mapping of RNA Modifications: Proceedings of a Workshop–in Brief One strategy cells use for regulation is modifying proteins, DNA, and RNA to control their structure, ...