Neuroblastoma is a highly lethal childhood cancer that develops in the peripheral nervous system with tumour growth fuelled by the biosynthesis of polyamines. The drug difluoromethylornithine, which ...

More than 95% of the 101,000 children who died in 2019 of respiratory syncytial virus lived in less wealthy countries.

At industrial scales, chemical reactions are typically driven by applying continuous heat to the reactants. In this week’s issue, Liangbing Hu and his colleaguesshow that pulsed heating and quenching ...

The cover shows Yournina Akinyi using her mobile phone at her produce stand in Matasia village, Kenya. In this week’s issue, Joshua Blumenstock and his colleagues show how big data derived from mobile ...

For more than 50 years, scientists have been trying to understand the relationship between DNA sequence, gene-expression phenotype and fitness to decipher principles of gene regulatory evolution. In ...

Inscriptions provide an invaluable insight into the ancient world. But over the centuries, many inscriptions have been damaged and exist in fragmented or semi-legible forms, making the job of reading ...

Many potential applications for artificial intelligence require making real-time decisions. Car racing, in which drivers must undertake complex tactical manoeuvres while controlling their vehicle at ...

The US National Cancer Act of 1971 has fostered tremendous progress in our understanding of the biology that underlies cancer. However, scientific and social challenges remain. A new action plan to ...

The seven planets orbiting the star TRAPPIST-1 were largely spared cosmic collisions, raising questions about where these worlds got their water.

Pure mathematics involves the discovery of patterns between mathematical objects and using these connections to formulate conjectures. Mathematicians have deployed computers since the 1960s to help ...

Soft robots have garnered significant attention in recent years, thanks to their ability to carry out a range of complex tasks such as gripping, crawling or swimming. But making these soft actuators ...

The protein tau is believed to stabilize the skeleton that shapes nerve cells, but in neurodegenerative diseases known as tauopathies, tau misfolds and stacks together to form filaments. In this ...