Structural studies of less abundant proteins by in-cell NMR may however also be feasible, because 74% and 61% of the NOE cross-peaks used for the structure calculation could be still observed from ...

The structure of the membrane anchor domain of the bacterial autotransporter YadA is solved by a solid-state NMR spectroscopy approach using a uniformly 13C- and 15N-labeled microcrystalline sample.

‘13C APSY-NMR for sequential assignment of intrinsically disordered proteins’ — Murrali MG, Schiavina M, Sainati V, Bermel W, Pierattelli R, Felli IC, Journal of Biomolecular NMR, 2018.

Proteins are central to many disciplines within the life sciences, not least protein-based pharmaceuticals. Changes in protein conformation, structure or interactions could have significant impact on ...

In particular, Dr. Rosenbaum and his laboratory use protein engineering, X-ray crystallography, and NMR spectroscopy to study the structure and dynamics of molecules involved in hormone signaling ...

Another high-resolution method is nuclear magnetic resonance (NMR) spectroscopy, which can be used to characterize protein structure in liquids. However, this method is only practical when ...

Discover how vibration isolation enhances the accuracy and reliability of NMR spectroscopy by minimizing external ...

Including the Ensemble of Unstructured Conformations in the Analysis of Protein's Native State by High‐Pressure NMR Spectroscopy. Angewandte Chemie International Edition , 2024; DOI: 10.1002 ...

Researchers from Karlsruhe Institute of Technology (KIT) and Voxalytic GmbH have developed a new method that allows, for the first time, the elucidation of the chiral structure of molecules—the ...