and the resolution of microarrays, which often allowed scientists to identify only large genomic changes. 14 The advent of next-generation sequencing (NGS) and its combination with ChIP offered ...

and loss of heterozygosity (LOH)—including in mosaic samples—the panel combines the benefits of NGS and microarrays in one cost-effective assay. OGT’s CytoSure brand is renowned for excellence in ...

these features enable true high-throughput sequence capture for large-scale NGS studies. We optimized and streamlined all aspects of our protocols for genomic DNA microarray hybridization to allow ...

Expert Rev Mol Diagn. 2013;13(6):601-611. In other situations, normal microarray analysis in the presence of an abnormal karyotype, such as marker chromosomes, is reassuring, as it indicates that ...

Personalized Medicine. 2014;11(6):581-592. NGS is still predominantly used in a research setting, which is due to the lack of guidelines for sample processing and data analysis as well as missing ...

Deep sequencing technology could soon be competitive with certain array applications. But the jury remains out on which of the myriad platforms will have the greatest impact and broadest application.