Using a clever design embedding protein spacers between the antibody and the nucleosomes ... Next, 60 µL of 34 nM nucleosome arrays formed on the biotinylated 19-mer 200 bp 601 DNA were mixed with the ...

Polyphosphate (polyP) exists in all life forms; however, its biological functions in metazoans are understudied. Here, we explored Drosophila as the first genetic model to explore polyP biology in ...

While everyone’s blood contains the same basic parts, there are eight different blood types. The type you have depends on genes you inherit from your biological parents. What makes your blood ...

Autoimmune diseases are often associated with autoantibodies that abnormally target self-antigens (autoantigens). An intuitive therapeutic strategy for diseases caused by aAbs is to design decoys, or ...

In this review, we specifically focus on the recently described tolerance break and B cell abnormalities, as well as consequent molecular and cellular mechanisms of autoantibody production in patients ...

Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan Nagoya University Institute for Advanced Research, Advanced Analytical and Diagnostic Imaging Center (AADIC)/Medical Engineering ...

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