Deebo Samuel revealed why San Francisco quarterback Brock Purdy was upset after Sunday's win over the Tampa Bay Buccaneers.

While it’s certainly a positive that the reigning Offensive Player of the Year is back in their lineup, the club now has to ...

Star pass-catcher George Kittle and the San Francisco 49ers face the Seattle Seahawks on Sunday at 4:05 p.m. ET, at Levi’s ...

Christian McCaffrey returned to San Francisco 49ers practice on Wednesday with a clean bill of health after making his season ...

A handful of players were absent from the first Week 11 practice for the 49ers with four of them being star players.

Tampa Bay Buccaneers Tackle Luke Goedeke was mic'd up for Week 10's Salute to Service game against the San Francisco 49ers. Hear from Luke in this week's edition of Mic'd Up.

This did not escape two of Mayfield's big media fans, Fox sideline reporter Erin Andrews and studio host Charissa Thompson.

The San Francisco 49ers earned a hard-fought victory on Sunday against the Tampa Bay Buccaneers, securing back-to-back wins ...

Christian McCaffrey certainly showed flashes of greatness Sunday during his season debut. But as a runner, he was not the ...

Moody was a controversial selection when the 49ers picked him--a third-rounder is an extraordinarily high pick to use on a ...

Listen in as players from the 49ers locker room shared their excitement for DB Deommodore Lenoir's five-year contract ...

San Francisco 49ers quarterback Brock Purdy was announced as NFL Slimetime's "Nickelodeon Valuable Player" for Week 10.