A new human liver organoid platform could help predict which drugs trigger dangerous immune reactions in susceptible patients ...

Explore the impact of lysosomal lipid recycling in a rare multi-organ disorder linked to the SPNS1 gene mutations.

New research has discovered how Rab proteins control the delivery of critical supplies to strengthen neural connections, providing researchers with important insights into memory formation and ...

AI has advanced molecule design, yet synthetic feasibility remains a bottleneck. Chemistry-first approaches offer a practical ...

Drug discovery now costs 100 times more per FDA-approved drug than in 1950, despite vast advances in biology and computing. The core problem is the collapse of predictive validity in preclinical ...

14 October 2025 | By Dr Jack Scannell (CEO of Etheros Pharmaceuticals Corp), Dr Raminderpal Singh (Hitchhikers AI and 20/15 Visioneers) Drug discovery now costs 100 times more per FDA-approved drug ...

New research has demonstrated how tiny tweaks in a DNA-sensing enzyme may hold the key to the naked mole-rat’s extraordinary lifespan – offering insights that could one day inform therapies for aging ...

The rise of personalised cancer immunotherapy represents a pivotal shift in oncology, aiming to harness the body’s own immune system to recognise and eliminate tumour-specific neoantigens. Encouraging ...

Explore the challenges of CNS drug development for neurodegenerative diseases and the complexity of measuring disease ...

Scientists have developed a new gene therapy that reversed symptoms of SYNGAP1-related brain disorders in mice, which could lead to new treatments for this group of neurological conditions. This is ...

Scientists have developed a new gene therapy that reversed symptoms of SYNGAP1-related brain disorders in mice, which could lead to new treatments for this group of neurological conditions.