The Genomic and RNA Profiling core offers various RNA-seq chemistries for many sample types. Total RNA-seq: Capture of both coding and non-coding RNAs. Compatible with degraded RNA. Full-length ...

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive ...

Researchers working with RNA-seq face a major challenge: ribosomal RNA (rRNA). While rRNA can comprise up to 90% of a total RNA sample, in most cases, it doesn’t provide information about the ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq ...

In total RNA sequencing experiments, many reads are not necessarily useful or desired for gene expression studies, including intronic reads from pre-mRNA or noncoding transcripts. Using target ...

RNA sequencing is particularly useful to identify ... The kit allows researchers to carry out a total nucleic acid extraction from any sample type: FFPE samples, cells, tissues or biofluids ...

This mismatch can overemphasize cell types with high total gene expression and underemphasize those with low expression in the bulk RNA-seq deconvolution. Similar issues arise from differences in ...

A research team has uncovered new insights into the molecular mechanisms of ADAR1, a protein that regulates ribonucleic acid (RNA) induced immune responses. Their findings could open new pathways for ...