The Genomic and RNA Profiling core offers various RNA-seq chemistries for many sample types. Total RNA-seq: Capture of both coding and non-coding RNAs. Compatible with degraded RNA. Full-length ...

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive ...

Researchers working with RNA-seq face a major challenge: ribosomal RNA (rRNA). While rRNA can comprise up to 90% of a total RNA sample, in most cases, it doesn’t provide information about the ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq ...

In total RNA sequencing experiments, many reads are not necessarily useful or desired for gene expression studies, including intronic reads from pre-mRNA or noncoding transcripts. Using target ...

RNA sequencing is particularly useful to identify ... The kit allows researchers to carry out a total nucleic acid extraction from any sample type: FFPE samples, cells, tissues or biofluids ...

With the long-term goal of creating living cells from non-living components, scientists in the field of synthetic biology ...

A research team has uncovered new insights into the molecular mechanisms of ADAR1, a protein that regulates ribonucleic acid (RNA) induced immune responses. Their findings could open new pathways for ...

This mismatch can overemphasize cell types with high total gene expression and underemphasize those with low expression in the bulk RNA-seq deconvolution. Similar issues arise from differences in ...