Single-cell transcriptomics has revolutionized the study of cellular diversity and function by enabling gene expression ...

Researchers at Fred Hutch Cancer Center have discovered an overlooked mechanism driving aggressive breast and brain tumors ...

Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital and, Harvard Medical School, Boston, Massachusetts 02139, United States ...

Recently, several recent studies have shown that RNA methylation is closely related to cancer cell aging. 8-Oxoguanine (o 8 G) is an important and widely distributed methylation modification whose ...

In particular, RNA-targeting CRISPR-Cas13 proteins are promising single-effector systems to regulate target mRNAs without altering genomic DNA, yet the current Cas13 systems are restrained by ...

Get Instant Summarized Text (Gist) CRISPR gene editing has been used to explore the role of cis-regulatory sequences in the expression of the Unusual Floral Organs (UFO) gene, which is crucial for ...

Composite photograph of beads weighing an average of 0.0708 grams and measuring 5 millimeters in diameter, taken from a ton of scallops found at the Montelirio site in southern Spain. D.W.W. The ...

NGS is a high throughput technology that rapidly sequences large volumes of DNA or RNA, enabling comprehensive ... acid extractions with magnetic beads. In the subsequent NGS library prep step ...

United States Center for RNA Technologies and Therapeutics, University of California San Diego, La Jolla, California 92037, United States Chemical Genomics Centre, Max Planck Institute of Molecular ...

The fragmented RNA was then purified using 40 μl of MagicPure RNA Beads (TransGen). Each RNA sample was subsequently divided into two halves, with one half used for proximity ligation and crosslink ...