The fight against the global COVID-19 pandemic is one of the greatest challenges currently facing mankind. The international Covid19-NMR consortium aims to determine the dynamics, function and ...
Intrinsically disordered proteins (IDP) are proteins that lack tertiary structure. They are now being recognized as biologically crucial in both healthy systems and the pathophysiology of various ...
NEWARK — Determining exactly how proteins connect with specific DNA sequences in human cells has eluded researchers and scientists for years. While it has been possible to record the speed at which a ...
NMR makes use of specific stable isotopes, commonly 13 C, but there is only one NMR-active stable isotope for oxygen, 17 O. The effects of using this oxygen isotope over other isotopes include lower ...
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Spectroscopy and AI method provide unique window into protein structure and mechanism of action
The lab of Hassane Mchaourab, director of the Center for Applied Artificial Intelligence in Protein Dynamics and professor of molecular physiology and biophysics, has developed a methodological ...
The yeast prion protein Sup35NM is a self-propagating amyloid. Despite intense study, there is no consensus on the organization of monomers within Sup35NM fibrils. Some studies point to a β-helical ...
An industry–academia collaboration has led to the development of a tool that combines infrared and proton NMR spectroscopy ...
Discover how drug development targeting ion channels could be transformed with a new technique using nuclear magnetic ...
SDSC provides high-performance computing and data infrastructure that support researchers doing molecular modeling and ...
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