Demi Moore tells PEOPLE she hadn't met Margaret Qualley before becoming her costar in Coralie Fargeat’s new horror movie 'The Substance,' but had enough 'indirect connections' that they 'felt like we

The new body-horror movie "The Substance" is a wild time, It also took co-stars Demi Moore and Margaret Qualley way out of their comfort zones.

When it comes to upcoming horror movies, one of this year’s best may be hitting theaters this weekend, with Demi Moore ’s body horror flick The Substance causing quite a stir amongst critics since its premiere at Cannes.

"The Substance," in theaters Friday, is a twisted fountain of youth parable with bravura performances from Demi Moore and Margaret Qualley.

Demi Moore’s new horror movie “The Substance" tackles Hollywood's impossible beauty standards, something Moore has dealt with since her career began.

The actress stars alongside Margaret Qualley and Dennis Quaid in Coralie Fargeat’s gleefully grotesque movie about an aging celebrity who takes an experimental drug that gives her a younger self.

She and costar Margaret Qualley also devoted time to perfecting sexualized gyrations their celebrity fitness characters would perform in front of leering cameras and a slimeball of a boss, played by Dennis Quaid,

The Substance, the new film starring Margaret Qualley and Demi Moore, has set a record for the latter. The body-horror film follows a fading celebrity (played by Moore) who begins to use a black-market drug that creates a younger version of herself (Qualley).