The authors have demonstrated the use of adenine base editors delivered via adeno-associated viruses to introduce edits in the mitochondrial genome. The manuscript describes the methodology well, and ...

Shah and colleagues take advantage of the presence of maternal and somatic ribosomes in zebrafish and confirm their differential expression during development. The authors convincingly show that ...

A new article in the journal Nucleic Acid Therapeutics addresses the recognition by the U.S. Food and Drug Administration ...

2014). For cell culture, RPMI medium 1640 (RPMI; Invitrogen Life Technologies, Rockville, MD) and Dulbecco's modified Eagle's medium (DMEM; Invitrogen Life Technologies) were supplemented with 10% ...