The gold standard technology that scientists use to detect DNA methylation is bisulfite genomic sequencing. It is a qualitative, quantitative, and efficient approach to identify methylated cytosine at ...

A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA ...

A multi-institutional team of bioengineers has identified the genetic mechanism that converts bitter toxins to palatable ...

A comprehensive atlas maps DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation.

Chromatin immunoprecipitation sequencing allows for genome-wide profiling of protein-DNA interactions and of histone PTMs. GARP offers ChIP-seq library construction starting with ChIP and Input DNA.

Pairing bisulfite conversion of the human genome with targeted enrichment and high-throughput sequencing allows a quantitative assessment of DNA methylation at base-pair resolution. A DNA molecule ...

Among the various approaches, bisulfite sequencing is the most widely adopted. The process involves treating a DNA sample with sodium bisulphate, which has the effect of making methylated cytosine ...

In this GEN webinar, our expert speaker Dave Lahr, PhD, Senior Director of Bioinformatics at Foghorn Therapeutics, will describe how chromatin mapping assays such as CUT&RUN, ATAC-seq, and bisulfite ...

1 Following bisulfite conversion, researchers determine the methylation status in loci of interest because unmethylated cytosines are recognized as thymine after PCR amplification and sequencing. 3 ...