The gold standard technology that scientists use to detect DNA methylation is bisulfite genomic sequencing. It is a qualitative, quantitative, and efficient approach to identify methylated cytosine at ...

A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA ...

A multi-institutional team of bioengineers has identified the genetic mechanism that converts bitter toxins to palatable ...

Their findings, as their Science Advances study explains, points to a “complex epigenetic and genetic network” of transformations that allow humans and many animals to eat tomatoes without fear.

A comprehensive atlas maps DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation.

Among the various approaches, bisulfite sequencing is the most widely adopted. The process involves treating a DNA sample with sodium bisulphate, which has the effect of making methylated cytosine ...

Chromatin immunoprecipitation sequencing allows for genome-wide profiling of protein-DNA interactions and of histone PTMs. GARP offers ChIP-seq library construction starting with ChIP and Input DNA.

Pairing bisulfite conversion of the human genome with targeted enrichment and high-throughput sequencing allows a quantitative assessment of DNA methylation at base-pair resolution. A DNA molecule ...

In this GEN webinar, our expert speaker Dave Lahr, PhD, Senior Director of Bioinformatics at Foghorn Therapeutics, will describe how chromatin mapping assays such as CUT&RUN, ATAC-seq, and bisulfite ...

1 Following bisulfite conversion, researchers determine the methylation status in loci of interest because unmethylated cytosines are recognized as thymine after PCR amplification and sequencing. 3 ...