This article explores 6-base genome sequencing and how it is empowering researchers to expand their studies to include both ...

Researchers have developed a comprehensive atlas that maps DNA methylation—a critical chemical modification governing gene ...

A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA ...

TAPS enables direct and high-fidelity methylation mapping with significantly reduced template damage and noise compared to conventional bisulfite sequencing, unlocking new possibilities for ...

We referenced bisulfite sequencing PCR, an assay established by Matthias Schaefer et al. We chemically deaminated cytosine in RNA using the EZ RNA methylation kit (50) (ZYMO RESEARCH) and then ...

Importantly, all studies reporting on actual transcript numbers that were m5C-modified relied on RNA bisulfite sequencing, an NGS-based method, that can discriminate between methylated and ...

This study, published in the Genes and Diseases journal by researchers at Sichuan University and Stanford University, used capture-based bisulfite sequencing to investigate the DNA methylation ...

A multi-institutional team of bioengineers has identified the genetic mechanism that converts bitter toxins to palatable ...

Their findings, as their Science Advances study explains, points to a “complex epigenetic and genetic network” of transformations that allow humans and many animals to eat tomatoes without fear.