The rapid identification of respiratory virus outbreaks is needed to enable rational and effective public health interventions. We developed new quantitative approaches for simultaneous ...

The recent breakthroughs in next-generation sequencing technologies, such as those of Roche 454, Illumina/Solexa, and ABI SOLID, have dramatically reduced the cost of producing short reads of the ...

As part of a global, multiyear agreement, Thermo Fisher Scientific today announced it is working with AstraZeneca to develop a solid tissue and blood- ...

Currently, the field is dominated by machines from Roche, Illumina (HiSeq2000), and ABI (SOLiD). 5 Each of these platforms is capable of performing whole genome sequencing, whole exome sequencing, RNA ...

Ze-Guang Han and colleagues report exome sequencing of ten hepatitis B virus–positive hepatocellular carcinomas. They identify recurrent somatic mutations in ARID1A and mutation signatures that ...

In 2010, SeqWright added the Illumina HiSeq 2000 sequencing system and informatics software to its already established Roche 454 GS FLX Titanium, Applied Biosystems SOLiD 4 sequencing platforms ...

New solutions are expected help mitigate bottlenecks in sample prep for next-generation sequencing. Caliper Life Sciences announced the availability of automation protocols on its Sciclone® NGS ...

Massively-parallel sequencing of small RNAs isolated from the myeloblasts of AML1 was performed using the ABI SOLiD sequencing platform. Pooled RNA isolated from CD34+ bone marrow cells of 4 healthy ...

DNA sequencing was conducted with a next-generation sequencing platform (the SOLiD System by Applied Biosystems) and involved ligation-based sequencing and a 2-base encoding method in which 4 ...

Applied Biosystems, now part of Invitrogen, was the first to pioneer a sequencing-by-ligation process, marketing it under the name of SOLiD. The process has some interesting features and is the ...