Cardinals running back James Conner has been ruled out ahead of Arizona's season finale against the San Francisco 49ers.

Conner initially suffered a right knee injury on a tackle in the third quarter of the Cardinals’ Week 16 loss to the Panthers. He did not return to the game but after three limi

SOFI STADIUM -- Arizona Cardinals RB James Conner is questionable to return to Week 17's battle against the Los Angeles Rams with a knee injury. Conner was questionable with a knee injury heading into Saturday after being a limited participant on all three days - he initially suffered the injury in last week's loss against the Carolina Panthers.

The Arizona Cardinals have ruled out running back James Conner ahead of their Week 18 finale against the San Francisco 49ers. Head coach Jonathan Gannon ruled Conner and Joey Blount when speaking with reporters on Wednesday.

Running back Michael Carter was signed from the practice squad, joining DeeJay Dallas, to make it two runners on the active roster. Tony Jones Jr. is a candidate to be elevated from the practice squad for Sunday’s game. Hassan Hall was signed to the practice squad Tuesday.

The Cardinals placed running back James Conner on injured reserve on Wednesday, per ESPN's Adam Schefter, sidelining him for Arizona's

Conner exited last Sunday's loss to the Carolina Panthers, which officially ended Arizona's playoff dreams, after suffering the injury in the third quarter. The offense sorely missed his production in the second half and overtime period. Kyler Murray and company hope he is able to return to the backfield for the final stretch of the season.

The Cardinals' disappointing season will wrap up against the 49ers in Week 18 but James Conner will miss the game with a knee injury.

The Arizona chapter of the PFWA named James Conner and Budda Baker co-MVPs and named Michael Wilson the season’s “good guy” with the media.

Cardinals RB James Conner is questionable to play Saturday against the Rams. Here’s the latest news on his status.

The Arizona Cardinals concluded their NFL regular season schedule with a decisive 47-24 victory over the San Francisco 49ers Sunday at State Farm Stadium.

Arizona Cardinals running back James Conner has been ruled out of Sunday's game against the San Francisco 49ers due to a knee injury, coach Jonathan Gannon said Wednesday. Conner, 29,