As the importance and prevalence of oligonucleotide therapeutics continue to grow, so does the need for robust characterization methodologies throughout drug development and production. Given the ...

Fluorinated compounds are increasingly used in medicinal, agricultural, and material science applications. NMR probes and procedures were historically employed to get hydrogen and carbon spectra.

Intrinsically disordered proteins (IDP) are proteins that lack tertiary structure. They are now being recognized as biologically crucial in both healthy systems and the pathophysiology of various ...

Fragment-based drug discovery (FBDD) has emerged as a transformative approach in medicinal chemistry by focusing on the identification of small chemical fragments that bind to biologically relevant ...

NMR properties of nuclei / Klaas Hallenga and Alexander I. Popov -- Fourier-transform NMR : theoretical and practical aspects / Klaas Hallenga -- Solid state NMR of spin-1/2 nuclei / Robert A. Wind -- ...

Monoclonal antibodies are widely used to treat diseases ranging from cancer to autoimmune disorders. The safety and efficacy ...

NMR (Nuclear Magnetic Resonance) spectroscopy is a powerful analytical technique that provides detailed information about the structure, dynamics, and chemical environment of molecules at the atomic ...

Nuclear magnetic resonance (NMR) is an information-rich technique. However, it requires a higher analyte concentration than all other spectroscopic methods, especially when compared to analytical ...

Confluence of Major NMR Methods and Instrumentation Advances Enables Next-Generation GHz Technology with Focus on Structural Biology, Macromolecular Complexes, Membrane Proteins and Intrinsically ...

Researchers have achieved a breakthrough in zero-field nuclear magnetic resonance spectroscopy, paving the way towards benchmarking quantum chemistry calculations. What is the structure of a ...

A pair of grants from the Offices of the Provost and the Dean for Research (DfR) will transform materials science, synthesis, catalysis and chemical biology research across campus through the ...