Renal drug excretion involves filtration, reabsorption, and secretion, crucial for drug clearance and minimizing toxicity. The study models renal clearance using pharmacokinetic parameters, validated ...

Extract: This report concerns two patients with primary renal tubular acidosis (RTA) in whom the abnormality in hydrogen excretion was shown to result from inappropriate urinary loss of bicarbonate ...

HYPERCHLOREMIC acidosis is a characteristic feature of a variety of kidney diseases that have in common impairment of urinary acidification with the excretion of an alkaline urine. These disorders, ...