In a pair of studies, investigators from the lab of Huiping Liu, MD, Ph.D., associate professor of Pharmacology and of ...

In the march of metastasis, a molecular trail of crumbs guides some cancer cells from the primary tumor to establish new ...

Cancer cell biology unravels the molecular and cellular underpinnings of tumour formation, progression and metastasis. At its core, cancer arises as a result of dysregulated cell cycle control, ...

Pressure from surrounding tissues activates invasive programs in cancer cells. This mechanical stress rewires epigenetic regulation. Cancer cells are notoriously adaptable, capable of shifting their ...

Spatial biology first entered the omics scene about a decade ago. Since then, the technology has generated significant buzz both inside and outside of the lab—beyond its contributions to science. The ...

Telomere damage drives T cell exhaustion. Antioxidants restored their cancer-fighting strength in mice. Tumor environments place heavy stress on immune cells that fight cancer. Limited oxygen, ...

Researchers say findings offer potential therapeutic implications for both bone metastasis and cancer-associated anemia.

Unlike traditional approaches that typically test one protein target or drug at a time in hopes of identifying an effective ...

When Ph.D. student Kshitiz Parihar began combing through dozens of research papers on two seemingly different topics — tumor ...

Joseph Gall was posthumously recognized for the societal impacts of his basic research in molecular biology, guided by his ...

Urothelial carcinoma (UC) is the second most common genitourinary cancer, leading to over 16,000 deaths a year in the U.S. Despite recent advances, the five-year survival rate for metastatic UC ...