SportsLine's model revealed its college basketball predictions for Houston Cougars vs. Purdue Boilermakers on Friday in the Sweet 16 of the 2025 NCAA Tournament

The Houston Cougars and Purdue Boilermakers face off Friday night in a Sweet 16 NCAA Tournament matchup in Indianapolis. Houston (32-4) is favored by 8.5 point

The Cougars were tested and trailed at halftime, but rebounded in the second half with Milos Uzan's starring effort.

With 2.8 seconds left, Houston's execution provided another example of how Sampson’s mind calms in hectic moments to find simple solutions.

Milos Uzan was the third option on the drawn-up situation, but big man JoJo Tugler’s instincts made all the difference to advance the Cougars.

The Houston Cougars and Purdue Boilermakers battle in the Sweet 16 of the 2025 NCAA Men's Basketball Tournament on Friday, March 28.

Next up on the schedule: No. 4 Purdue and No. 1 Houston. Wondering who's calling this game on TBS on Friday night? Fear not! We have answers! Andrew Catalon will be on play-by-play duties. Steve Lappas will be there as the analyst. Evan Washburn will be reporting from the sidelines.

No. 4 Purdue plays No. 1 Houston in the Sweet 16 round of the NCAA Men's Basketball Tournament. Follow the live blog for in-game updates throughout the night.

Houston, Michigan State and Auburn came up clutch, while Tennessee was a bully from the start in Sweet 16 action Friday night.

No. 1 seed Houston advanced to the Elite Eight on a perfectly executed last-second inbounds play that led to a game-winning layup by Milos Uzan on Friday night, as the Cougars outlasted No. 4 seed Purdue 62-60 in a thrilling cap to the Sweet 16.