This is a preview. Log in through your library . Abstract In this article, regression splines are used inside linear mixed models to explore nonlinear longitudinal data. The regression spline bases ...

We describe and contrast several different bootstrap procedures for penalized spline smoothers. The bootstrap methods considered are variations on existing methods, developed under two different ...

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Single nucleotide polymorphism (SNP) interaction plays a critical role for complex diseases. The primary limitation of logistic regressions (LR) in testing SNP–SNP interactions is that coefficient ...