Nature

Design characteristic of randomised controlled trials for geographic atrophy in age-related macular degeneration: selection of outcomes and sample size calculation

The selection of suitable outcomes and sample size calculation are critical factors in the design of a randomised controlled trial (RCT). The goal of this study was to identify the range of outcomes ...
ascopubs.org

Bayesian Sample Size Planning Tool for Phase I Dose-Finding Trials

Implementation of the Time-to-Event Continuous Reassessment Method Design in a Phase I Platform Trial Testing Novel Radiotherapy-Drug Combinations—CONCORDE BayeSize applies the concept of effect size ...
ascopubs.org

Adaptive Cohort Size Determination Method for Bayesian Optimal Interval Phase I/II Design to Shorten Clinical Trial Duration

Improved Cancer-Specific Risk Stratification by the Lymph Node Ratio-Based Nomogram: A Potential Role in Guiding Postoperative Management Decisions for Oral Cavity Carcinoma We propose a novel ...
JSTOR Daily

The Determination of Sample Sizes for Use with the Exact Conditional Test in 2 x 2 Comparative Trials

Mainland and Sutcliffe [1953] and Bennett and Hsu [1960] have calculated the power of the exact conditional (Fisher-Irwin) test for differences between proportions. We have performed similar ...
JSTOR Daily

Sample Size Determination for Robust Bayesian Analysis

This article considers a robust Bayesian approach to the sample size determination problem. We focus on global Bayesian robustness that studies lower bound ($L_{n ...