A series of structures of the eukaryotic protein-synthesis machinery are imaged at high resolution in defined states of the elongation phase of protein synthesis. Analysis suggests that there are ...

Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

This image illustrates the process of gene transcription within a cell. The DNA double helix unwinds to expose a specific sequence, allowing RNA polymerase to synthesize a complementary pre-mRNA ...

Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate ...

The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...

Researchers at UCL and MRC London Institute of Medical Sciences have demonstrated that reducing naturally occurring errors in protein synthesis improves both health and lifespan in different model ...

A multinational research team has discovered a mysterious tubular structure—previously unknown in any organism—within ...

ReAberrant translation initiation at non-AUG start codons is associated with cancer and neurodegenerative diseases. Therefore, identifying how non-AUG translation is regulated differently from ...

According to researchers at the University of Illinois Chicago, the antibiotics used to treat common bacterial infections, like pneumonia and sinusitis, may also be used to treat human diseases, like ...