A team of researchers at the University of Cologne's Center for Biochemistry, together with the Bambino Gesù Pediatric Hospital in Rome, Italy, have discovered a fundamental biological mechanism that ...

Dandelion root extract has shown remarkable potential in laboratory tests against colorectal cancer cells, triggering ...

For the first time, researchers at Umeå University have observed the same type of programmed cell death in microalgae as in humans. The discovery, published in Nature Communications, shows that this ...

Scientists discover karyoptosis, a new cell death mechanism causing nuclear disintegration in Alzheimer's and frontotemporal ...

The delicate balance between cell death and regeneration is crucial for human health and longevity. Most mechanisms involved in programmed cell death (PCD) play a key role in normal tissue renewal and ...

ER stress is detected through specialized molecular sensors associated with the ER membrane that define different arms of the UPR 1,2. The most conserved sensor in eukaryotes is the inositol-requiring ...

This finding, he suggests, helps link the study of cell death in the worm and oncogenesis in people. "There were a number of papers that had suggested a relationship between cell death and oncogenesis ...

A team of researchers at the University of Cologne’s Center for Biochemistry, together with the Bambino Gesù Pediatric Hospital in Rome, Italy, have discovered a fundamental biological mechanism that ...

How can molecular structures be analyzed when the resolution of the techniques available is not sufficient? Researchers from the fields of physics, chemistry and medicine at Heinrich Heine University ...

Programmed cell death encompasses several regulated pathways—apoptosis, necroptosis, pyroptosis, autophagy-related cell death and ferroptosis—that maintain tissue homeostasis and serve as intrinsic ...

This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC ...