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Balancing treatment allocation for influential covariates is critical in clinical trials. This has become increasingly important as more and more biomarkers are found to be associated with different ...
We provide an asymptotic test to analyze randomized clinical trials that may be subject to selection bias. For normally distributed responses, and under permuted block randomization, we derive a ...
In summary, DA should be considered a valid alternative to randomisation or allocation via the random permuted blocks method, particularly for small to moderate-sized clinical trials with multiple ...
Randomization was performed with a permuted block design and was stratified by geographic region, diabetes status, estimated glomerular filtration rate (eGFR) of less than 60 ml per minute per 1. ...
Randomization will be carried out using the permuted block approach with stratification by cancer type, and patient-caregiver dyads will be assigned to the same study arm. Participants on both arms ...
Random assignment (stratified permuted block random assignment type) was generated from a validated computer-generated random assignment schedule. The primary end points were DFS in ITT and tumor ...