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Adrenomedullin as an immunomodulator of CD14+MerTK+ circulating monocytes in liver failure syndromes
Adrenomedullin is increased in acute liver failure syndromes (ALF and ACLF), and AMBP1 is, on the contrary, reduced, mirroring the severity of the disease expressed by the SOFA score. ADM affects ...
Monocytes, a special type of white blood cell, play an important role in the innate immune system and contribute to host defense in the blood by secreting large quantities of pro-inflammatory ...
(from left) Dr. Ibrahim Hawwari, Prof. Bernardo Franklin and Lukas Roßnagel discover new intercellular communication mechanism in which blood platelets, so-called thrombocytes, regulate the function ...
Data from mouse models and human lung tissue offer foundation for studies of dietary interventions in asthma subtype.
A new study published on the preprint server medRxiv* in June 2020 shows that the drug hydroxychloroquine (HCQ) suppresses a form of immunity called ‘trained immunity,’ with repercussions for its ...
Researchers have uncovered new evidence that challenges long-standing beliefs about asymptomatic malaria infections. The ...
Dr. Dobbs’ research interests include innate immunity to malaria and childhood infections of global health significance. She is currently principal investigator of a career development award studying ...
Liver failure syndromes are characterized by a dysregulated immune response leading to immune paralysis. Adrenomedullin (ADM) is a potent vasodilator and immunoregulator. This study aimed to explore ...
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