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Boston-based PerkinElmer Life and Analytical Sciences has released the prOTOF™ 2000, the first commercially available matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass ...

Novel Method to Finding New Drug Candidates with Promising Therapeutic Applications Over the last few decades, matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) has proven its ...

Detailed elucidation of protein structure and function typically requires removal of the protein from its in vivo environment. However, applying traditional and detergent-based protein extraction and ...

Drug discovery requires two separate steps: checking whether a drug can bind to a harmful molecule or its receptor, and ...

Atmospheric pressure (AP) MALDI is broadly used in the high-throughput mass analysis of lipids, peptides, and small molecule as well as MS imaging (MSI) studies. AP-MALDI is an affordable and quickly ...

Biotherapeutics such as monoclonal antibodies, fusion proteins, peptides and cytokines are increasingly complex, creating challenges for rapid and accurate quality characterization. Traditional liquid ...

Thanks to its easy and quick use, MALDI-TOF mass spectrometry has a significant analytical edge. The MALDI-TOF spectra of edible oils have multifaceted and delicate features that can be studied with ...

Using MALDI-TOF, researchers can quickly and accurately determine polymer, protein and nucleic acid masses. They can also analyze and resolve complex assortments of smaller peptides and ...

What are the ionization techniques for mass spectrometry? Mass spectrometry (MS) plays a vital role in many aspects of our lives, from diagnosing illness and detecting food contaminants to fighting ...