Neuroscientists have developed a statistical framework that rigorously describes the brain state changes that patients experience under ketamine-induced anesthesia. By developing the first statistical ...

Since Yale researchers first observed the ability of the anesthetic ketamine to dramatically improve symptoms in many patients with treatment-resistant depression more than two decades ago, the drug ...

New research demonstrates the effectiveness of ketamine to treat depression in a mouse model of the disease and brings together two hypotheses for the cause of depression. The research, led by ...

University of Arizona researchers have revealed new insights into the neurobiological cause of the involuntary, uncontrollable movement disorders that develop in patients with Parkinson’s disease (PD) ...

In recent years, media reports touting ketamine as a fast-acting, highly effective treatment for severe depression have increased. In part, this phenomenon is due to the US Food and Drug ...

These properties of NMDAR blockade offer useful opportunities to understand functional effects of ketamine on cortico-cortical and cortico-hippocampal large network, motor activity, cognitive ...

Ketamine is a short-acting general anesthetic that’s been around since the 1970s. It was first used in the United States for sedation and pain management during the Vietnam War. It continues to have ...

Ketamine infusion therapy as a treatment of clinical depression is still relatively new, but has been shown to have beneficial effects on clinically depressed patients. Not everyone who receives ...

Based on brain rhythm measurements from nine human and two animal subjects, the new model published in PLOS Computational Biology defines the distinct, characteristic states of brain activity that ...