The current literature is lacking on outcomes among patients with comorbid chronic rhinosinusitis (CRS) and immunoglobulin deficiencies, especially for those who must use surgery to manage their CRS.

Immunoglobulin deficiency, whether prevalent or acquired, was not correlated with the risk for severe infections, nor were levels of gammaglobulins, IgG, IgA, or IgM. Study limitations included ...

Following a blood infection, the first class of antibodies produced by the immune system are IgM antibodies. They form the "vanguard" of the immune response, before other cells are activated to fight ...

Low immunoglobulin levels affect nearly 1 in 4 newly diagnosed patients with diffuse large B-cell lymphoma (DLBCL) and significantly increase infection risk during treatment. Patients with low ...

Philadelphia, May 26, 2023—IgA deficiency is the most common primary immune deficiency worldwide, but its presentation has puzzled physcians and researchers. Some with the disorder present with ...

A firm handshake between proteins on immune cells is important for the body's ability to fight infection. Meanwhile, a weak grip helps explain the poor immune deficiencies caused by a rare genetic ...

A new study has demonstrated that IgA acts as a 'tuner' that regulates the number of microbes the body sees every day, restraining the systemic immune response to these commensal microbes and limiting ...