A fundamental challenge in preclinical research is accurately predicting human responses using conventional animal models. Traditional approaches often fail to adequately model human disease, creating ...

Understanding human gene function in living organisms has long been hampered by fundamental differences between species. Although mice share most protein-coding genes with humans, their regulatory ...

Genetically-humanized FcRn mice provide translational pharmacokinetics (PK) and pharmacodynamics (PD) data for antibody-based therapeutics. The image illustrates a therapeutic antibody (blue) adhering ...

Researchers are utilizing artificial intelligence to analyze the behavior of laboratory mice more efficiently and reduce the number of animals in experiments. Researchers at ETH Zurich are utilising ...

There is one specific task that stress researchers who conduct animal experiments need to be particularly skilled at. This also applies to researchers who want to improve the conditions in which ...