Researchers showed that in C. elegans, the protein MBD-2 regulates genes through repressive histone marks rather than DNA ...

Deep-learning model decodes the regulatory effects of DNA changes ...

Some genetic mutations that are expected to completely stop a gene from working surprisingly cause only mild or even no symptoms. Researchers in previous studies have discovered one reason why: cells ...

For decades, biologists have known that the instructions for life are written in DNA, yet the vast majority of those letters seemed to sit in the dark, doing little that was obvious. Now a new ...

First came AlphaFold. Now comes AlphaGenome for DNA. When scientists first sequenced the human genome in 2003, they revealed the full set of DNA instructions that make a person. But we still didn’t ...

It could transform our understanding of why diseases develop and the medicines needed to treat them, says researchers.

DNA is often called the blueprint of life, but what does that really mean? Elizabeth Worthey, Ph.D., associate professor, Department of Genetics in the Heersink School of Medicine, explains everything ...

A schematic showing the cytosine base editing intermediate and the various outcomes that can occur when the UNG protein is active. You may have seen it in the news recently: a baby in Pennsylvania ...

Researchers led by Min Zhang and Dabao Zhang of the University of California, Irvine's Joe C. Wen School of Population & ...

AI-powered gene maps reveal the hidden control centers driving Alzheimer’s disease — and point to new hope for treatment.