Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...
The Pol-theta enzyme (blue) joins two parts of a broken DNA strand (yellow). This process is mutagenic and can give rise to cancer. LA JOLLA, CA—DNA repair proteins act like the body’s editors, ...
A common hallmark of viral genome replication is a high mutation rate, which can aid in their ability to evade new treatments and acquire resistance to once-effective antiviral medications. Now, a new ...
From synthetic biology and gene therapy to data storage and biofuel production, the demand for synthetic DNA is rising. (1) Chemicals remove the 5’-hydroxyl protecting group. The nucleosides are rich ...
Researchers have reconstructed transcription in human mitochondria in unprecedented detail, revealing potential drug targets ...
DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers ...