G protein-coupled receptors (GPCRs) are expressed on the surface of cells and regulate a range of important functions. Because they are involved in so many sensory and physiological processes, ...
Researchers at Leipzig University and Martin Luther University Halle-Wittenberg have investigated a previously unknown ...
St. Jude announces $13 million investment to expand the understanding of G-protein coupled receptors
St. Jude Children's Research Hospital today announced a nearly $13 million investment toward a new research collaboration with scientists at Columbia University, Duke University and Stanford ...
By targeting a newly uncovered weakness in prostate cancer cells, this could offer an improved treatment for the disease.
Phase I Trial of MCARH109, a G Protein–Coupled Receptor Class C Group 5 Member D (GPRC5D)–Targeted Chimeric Antigen Receptor T-Cell Therapy for Multiple Myeloma: An Updated Analysis The following ...
From September 1, 2021, to March 23, 2022, 33 patients were infused with anti-GPRC5D CAR T cells. At a median follow-up of 5.2 months (range, 3.2‐8.9), the overall response rate was 91% (95% CI, 76 to ...
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