Next-generation sequencing (NGS) provides researchers from various scientific ... From new graduate students lacking wet bench experience to tenured professors trying bioinformatics for the first time ...

However, the latest next-generation sequencing techniques are able to produce longer reads from much larger fragments of DNA nucleotide strands. There are two well-established processes for the ...

“That's not bad, for the first go,” Deighton says. In the last few years, the next-generation sequencing platforms have been developed and sprung up in large sequencing facilities. But in ...

(Image: National Human Genome Research Institute) (click on image to enlarge) Developed by Frederick Sanger in the 1970s, Sanger sequencing was the first widely used method ... pattern of bands on the ...

Next-generation DNA sequencing has started a revolution in genomics and created the opportunity for large-scale sequencing projects, such as the recently announced 1,000 Genomes Project—an ...

Prospective real world data evaluation of clinical outcomes in metastatic hormone sensitive prostate cancer (MHSPC) patients treated as part of triplet therapy with darolutamide: UK multicenter ...

The MiSeq desktop sequencer offers low throughput flowcells and long read lengths. It is best for small whole-genome sequencing, targeted gene sequencing, metagenomics, and CRISPR validation. The ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical ...

Nanpore sequencing is a third-generation sequencing technology that generates long reads. Our Oxford Nanopore PromethION sequencer can sequence up to 24 flow cells simultaneously, each flow cell ...

"The association of homologous recombination repair defects with response to treatment with PARP inhibitors marked the first successful ... cancer by next-generation sequencing and functional ...

which is due to the lack of guidelines for sample processing and data analysis as well as missing or insufficient measures for quality of the sequencing results. The American College of Medical ...