FDA, ketamine and major depressive disorder

FDA approves standalone use of J&J's ketamine-derived depression treatment
The U.S. Food and Drug Administration has expanded the approval for Johnson & Johnson's nasal spray Spravato to allow its standalone use in patients with depression, the company said on Tuesday. The drug was previously approved in combination with antidepressants to treat symptoms in adults with major depressive disorder (MDD) who experienced suicidal thoughts or actions.
FDA approves Johnson & Johnson’s nasal spray for depression as standalone treatment
Spravato is now the first-ever standalone therapy for treatment-resistant depression, and is on its way to becoming a blockbuster product.
Safety and Feasibility of Intranasal Ketamine in Depression Treatment
The following is a summary of “Intranasal racemic ketamine maintenance therapy for patients with treatment-resistant depression: a naturalistic feasibility study,” published in the January 2025 issue of Psychiatry by Halpape et al.
US FDA approves J&J's ketamine-based therapy to treat depression
The U.S. Food and Drug Administration approved Johnson & Johnson's ketamine-based nasal spray Spravato, to treat adults with major depressive disorder, the company said on Tuesday.
J&J's ketamine-based nasal spray Spravato approved by US FDA to treat depression
The FDA approved Johnson & Johnson's Spravato, a ketamine-based nasal spray, to treat adults with major depressive disorder who have not responded to at least two oral antidepressants. This approval addresses the need for new options for treatment-resistant depression,
Research indicates recreational ketamine use is on the rise
Respondents who said they used other drugs recreationally were also likelier to say they used ketamine during the past year ...
Medscape1h
Ketamine-Induced Uropathy: What Urologists Need to Know
A multidisciplinary approach, including ketamine withdrawal and symptom management, is essential to mitigate long-term ...
US Weekly on MSN4d
What Celebrities and Doctors Have Said About Ketamine Use: Chrissy Teigen, Matthew Perry, More
Celebrities like Chrissy Teigen and Matthew Perry have been open about using ketamine for their mental health – here's what ...
health.wusf.usf.edu13d
Tiny fish on ketamine may show how drug eases depression
In zebrafish, ketamine causes changes a brain circuit involved in "giving up." That may help explain how the drug helps ...
Inquirer on MSN21h
Controlled drug Ketamine a lifeline for patients with severe depression in S’pore
Ketamine therapy is now a mainstream prescription for treatment-resistant depression. Read more at straitstimes.com.
IFLScience on MSN11d
Ketamine's Potential To Treat Depression Beautifully Shown In Struggling Zebrafish
Ketamine’s promising potential to ease depression is one of the reasons why its use has recently skyrocketed in the US and ...
What We Know About Musk's Ketamine Use
Musk himself has said he uses the drug to treat depression, and he's frequently posted about it on X generally over the years ...