If Jalen Hurts and the Eagles win against Washington Saturday, Dak Prescott and the Cowboys will be eliminated from playoff consideration. The game pits the Cowboys' elite passing offense against a Chargers' defense that has allowed less than 20 points in three straight games and ranks ninth in opposing points per game.

See who's in and who's out for the Week 16 matchup between the Dallas Cowboys and Los Angeles Chargers on December 21, 2025.

We know who will be on the field when the Dallas Cowboys host the Chargers in Week 16 of the 2025 NFL season, but who will be the voices in the booth?

Cowboys wide receiver CeeDee Lamb missed practice due to illness, while cornerback DaRon Bland missed practice with a foot injury.

The Dallas Cowboys are making multiple transactions on Wednesday leading up to Week 16 on the injury front. With only three weeks remaining in the 2025 regular season, the Cowboys announced they're opening three players' practice windows ahead of the team's matchup against the Los Angeles Chargers.

Los Angeles enters Week 16 having won six of its last seven games and sitting at 10-4, one victory away from clinching a playoff berth. The Bolts travel to AT&T Stadium on Sunday morning to face the Dallas Cowboys (6-7) with multiple clinching scenarios in play.

Here's everything you need to know when the Los Angeles Chargers play the Dallas Cowboys Week 16 of the 2025 NFL season.

Dallas Cowboys wide receiver George Pickens is facing criticism after totaling just 70 receiving yards over his last two games.