Nucleic acid (NA) based tests are increasingly being used across various disease conditions for diagnosis, prognosis, for treatment decisioning and can be scaled up very quickly in both central lab ...

Colorectal cancer (CRC) ranks as one of the most common malignancies globally 1. It evolves gradually from normal intestinal mucosa into benign precancerous adenomas, then to carcinoma, and ultimately ...

DNA and RNA methylation, initially thought to operate as distinct pathways, have been shown to interact closely, shifting our understanding of gene regulation. A team of researchers from the ...

CRISPR’s rise from obscure bacterial defense system to molecular scalpel has always hinged on one small component: the guide RNA. For years, that guide RNA—meticulously designed, modified, and ...

We’re celebrating 180 years of Scientific American. Explore our legacy of discovery and look ahead to the future. In 1957, just four years after Francis Crick and other scientists solved the riddle of ...

A team of engineers at the University of Florida has developed a new form of CRISPR technology that could make diagnostics and treatments safer, more precise and more affordable, while opening the ...