Post-traumatic osteoarthritis (PTOA) is caused by joint injuries leading to progressive degeneration of articular cartilage. PTOA is prevalent in young adults and acute symptoms include swelling, ...

Perlecan is a large heparan sulphate proteoglycan integral to the assembly, maintenance and mechanical responsiveness of cartilage. During embryonic and postnatal cartilage development, perlecan ...

Scientists have pinpointed 145 potential "height genes" in cells that make up the cartilage at the ends of children's bones and affect how tall they grow. These cartilage cells, known as chondrocytes, ...

For the first time, researchers have identified and characterized unique cell populations that form the superficial zone of human joint cartilage. The zone has the most critical role in cushioning the ...

Cartilage injury is a common cause of joint dysfunction and existing joint prostheses cannot remodel with host joint tissue. However, it is challenging to develop large-scale biomimetic anisotropic ...

In the event of a bone fracture, fatty acids in the blood signal to stem cells that they have to develop into bone-forming cells. If there are no blood vessels nearby, the stem cells end up forming ...

Researchers at the University of Southampton and the Centre for Human Development, Stem Cells, and Regeneration have developed a new method to generate human cartilage tissue from stem cells. The ...

Natural Field recently completed a Phase I scientific evaluation study on joint health functionality. The results ...

Sox9, a master regulator of cartilage formation, switches its target genes dynamically during embryonic limb development instead of following a fixed program, as reported by researchers from Science ...

In the event of a bone fracture, fatty acids in our blood signal to stem cells that they have to develop into bone-forming cells. If there are no blood vessels nearby, the stem cells end up forming ...

In the event of a bone fracture, fatty acids in our blood signal to stem cells that they have to develop into bone-forming cells. If there are no blood vessels nearby, the stem cells end up forming ...