Researchers at Leipzig University have developed a new process for reversing the polarity of chemical compounds, also known as umpolung, for the precise synthesis of pharmaceuticals.

Researchers at Leipzig University have developed a new process for reversing the polarity of chemical compounds, also known as umpolung, for the precise synthesis of pharmaceuticals. This innovative ...

1). The result was striking. Despite the absence of the carbonyl group at C41, the synthetic probe proved to be equipotent to the parent natural product. Deletion of the sugar moieties from either ...