Researchers have discovered a type of "molecular glue" that can be used to inhibit certain pathological protein interactions. Their findings were published in the paper, "Molecular glues that inhibit ...

BRCA—the family of DNA-repair proteins associated with breast, ovarian prostate, and pancreatic cancers—interacts with a multipart, molecular complex that is also responsible for regulating the immune ...

The Structure of BRISC in association with SHMT2. BRISC-SHMT2 complexes were solved using cryo-electron microscopy. The BRISC deubiquitylase complex is a U shaped dimer. Each side of this symmetrical ...

When there is an excessive number or hyperactivation of immune cells, very high levels of proteins known as cytokines are released, resulting in a cytokine storm that causes severe and often ...