Researchers at the Perron Institute and The University of Western Australia have discovered a new set of cells that can protect blood vessel structure in the central nervous system (CNS) known as the ...
The blood–brain barrier (BBB) is meant to protect the brain from noxious agents; however, it also significantly hinders the delivery of therapeutics to the brain. Several strategies have been employed ...
The cGAS-STING pathway is emerging as a key driver of chronic neuroinflammation through its effects on glial activation, ...
Within the neurovascular unit, neurons, glial cells, brain microvascular endothelial cells, and pericytes all harbor ...
Oligonucleotide therapeutics, including antisense oligonucleotides and small interfering ribonucleic acid (RNA), have emerged as powerful tools for regulating gene expression and treating neurological ...
In a pioneering achievement, a research team led by experts at Cincinnati Children's has developed the world's first human mini-brain that incorporates a fully functional blood-brain barrier (BBB).
Diseases such as Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease affect millions of people around the ...