The gold standard technology that scientists use to detect DNA methylation is bisulfite genomic sequencing. It is a qualitative, quantitative, and efficient approach to identify methylated cytosine at ...

A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA ...

A multi-institutional team of bioengineers has identified the genetic mechanism that converts bitter toxins to palatable ...

Their findings, as their Science Advances study explains, points to a “complex epigenetic and genetic network” of transformations that allow humans and many animals to eat tomatoes without fear.

A comprehensive atlas maps DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation.

Chromatin immunoprecipitation sequencing allows for genome-wide profiling of protein-DNA interactions and of histone PTMs. GARP offers ChIP-seq library construction starting with ChIP and Input DNA.

Among the various approaches, bisulfite sequencing is the most widely adopted. The process involves treating a DNA sample with sodium bisulphate, which has the effect of making methylated cytosine ...

Pairing bisulfite conversion of the human genome with targeted enrichment and high-throughput sequencing allows a quantitative assessment of DNA methylation at base-pair resolution. A DNA molecule ...

This study, published in the Genes and Diseases journal by researchers at Sichuan University and Stanford University, used capture-based bisulfite sequencing to investigate the DNA methylation ...

In this GEN webinar, our expert speaker Dave Lahr, PhD, Senior Director of Bioinformatics at Foghorn Therapeutics, will describe how chromatin mapping assays such as CUT&RUN, ATAC-seq, and bisulfite ...

Researchers have developed a comprehensive atlas that maps DNA methylation—a critical chemical modification governing gene ...