In this episode of Teach Me in 10, Dr. Christin Radon, a Biacore and Reagents Application Specialist at Cytiva, explains the ...

To choose the best lead candidates during drug and antibody screening, scientists characterize a molecule’s binding properties, such as kinetics and affinity. Robust assay design reduces experimental ...

BRANFORD, Conn.--(BUSINESS WIRE)--Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), a proteomics technology company redefining ...

A range of biophysical techniques is used in combination with computational analysis to understand whether glutamine-binding protein binds its ligand via the induced-fit or conformational selection ...

Determining and evaluating the affinity of small molecule binding to a therapeutic target is a major component of drug discovery and lead optimization. In a technical note entitled “Label-free ...

Rapid mixing accessories designed to conduct stopped flow measurements are utilized to characterize interactions and reactions occurring in solution. Reactants are expelled from syringes, mixed, and ...

Surface plasmon resonance (SPR) has revolutionized the study of the intricate protein interactions that are required for the execution and maintenance of complex biological processes, enabling the ...

Grating-coupled interferometry (GCI) is a surface based, a label-free optical sensing technique used for real-time binding kinetic measurements. 1 Typically, GCI is used to detect binding events ...

Biomolecular interactions are at the core of drug discovery and development. In order to accurately determine a biomolecular interaction’s affinity, binding kinetics and thermodynamic profile, among ...

How can treating neurological disease overcome challenges like the synthesis of small molecule agents that penetrate the blood-brain barrier, in order to sustain target engagement at low drug ...