Scientists have created a new way to map how brain cells connect by assigning each neuron a unique molecular “barcode.” Using ...

Janelia researchers developed an innovative new technique – cycleHCR -- that uses a novel DNA barcode system to track hundreds of RNA and protein molecules in single cells within thick biological ...

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems. Now an interdisciplinary ...

Nucleic acid-based therapeutics, including antisense oligonucleotides (ASO), small interfering RNA (siRNA), messenger RNA (mRNA), immunomodulatory DNA/RNA, and gene-editing guide RNA (gRNA), hold ...

The approach could expand understanding not only of the layout of elaborate networks in the brain, but also how the brain functions, what happens when there is dysfunction and how neurodegenerative ...